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Search Results for " Hepatitis C virus "

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カタログ番号	製品名	別名	ターゲット
T39503	Hepatitis Virus C NS3 Protease Inhibitor 2
	Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by ...
T25268	Coblopasvir		Others
	Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.		Others
T17190	U18666A		Others , HCV Protease
	U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.		Others , HCV Protease
T5938	4-Phenoxybenzylamine		HCV Protease
	4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .		HCV Protease
T9577	HCV-IN-31		HCV Protease
	HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM.		HCV Protease
T16088	MK-0608		HCV Protease
	MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay).		HCV Protease
T6846	Vesatolimod	GS-9620	Apoptosis , HCV Protease , HBV , TLR , HIV Protease
	Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.		Apoptosis , HCV Protease , HBV , TLR , HIV Protease
T25268L	Coblopasvir dihydrochloride	Coblopasvir dihydrochloride(1312608-46-0 Free base)	HCV Protease
	Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.		HCV Protease
T11539	HCV-IN-29		HCV Protease
	HCV-IN-29 is a hepatitis C virus (HCV) inhibitor.		HCV Protease
T38237	2′-O-Methylcytidine		Nucleoside Antimetabolite/Analog , HCV Protease
	2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G....		Nucleoside Antimetabolite/Analog , HCV Protease
T11541	HCV-IN-30		Others , HCV Protease
	HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).		Others , HCV Protease
T15573	Inarigivir soproxil	SB9200	HCV Protease
	Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype ...		HCV Protease
T4544	Elbasvir	MK-8742	HCV Protease
	Elbasvir (MK-8742) is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) being developed as a component of treatment regimens for chronic HCV infection.		HCV Protease
T3444	Merimepodib	VX-497,VI-21497	Dehydrogenase , Antiviral , HCV Protease , HBV
	Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).		Dehydrogenase , Antiviral , HCV Protease , HBV
T7215	NM107	NM-107,2'-C-Methylcytidine	HCV Protease
	NM107 (2'-C-Methylcytidine) is a ribonucleoside with broad-spectrum antiviral activity, is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, NM 107 in the wild-type replicon cells with the EC50 of 1...		HCV Protease
T0013	Mecarbinate	Dimecarbine,Dimecarbin	HCV Protease
	Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.		HCV Protease
T1565	Deferiprone	Deferidone,CP20	Others , HCV Protease , Ferroptosis , UGT
	Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.		Others , HCV Protease , Ferroptosis , UGT
T7158	Ombitasvir	ABT-267	HCV Protease
	Ombitasvir (ABT-267) is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype ...		HCV Protease
T76524	Hepatitis C Virus S5A/5B
	Hepatitis C Virus S5A/5B, a synthetic peptide substrate, replicates the NS5A/5B junction of the nonstructural protein (NS), serving as the substrate for examining HCV NS3 protease activity [1].
T14489	Azvudine	FNC,RO-0622	HCV Protease , HBV , HIV Protease , Reverse Transcriptase
	Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1...		HCV Protease , HBV , HIV Protease , Reverse Transcriptase
T1822	Clemizole		HCV Protease , Histamine Receptor
	Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.		HCV Protease , Histamine Receptor
T4547	Grazoprevir	MK-5172	HCV Protease , SARS-CoV
	Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), ...		HCV Protease , SARS-CoV
T5126	Glecaprevir	ABT-493	HCV Protease , SARS-CoV
	Glecaprevir (ABT-493) is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).		HCV Protease , SARS-CoV
T6200	Ledipasvir	GS-5885	HCV Protease , SARS-CoV
			HCV Protease , SARS-CoV
T3334	Velpatasvir	GS-5816	HCV Protease , SARS-CoV
	Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 d...		HCV Protease , SARS-CoV
T11281L	FGI-106 tetrahydrochloride		Virus Protease , HCV Protease , Influenza Virus , HIV Protease

T11760	KIN101	3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene	HCV Protease , Influenza Virus , RSV , Antifection
	KIN101 (3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene), an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has antiviral activity against RNA viruses, HCV, and R...		HCV Protease , Influenza Virus , RSV , Antifection
T9341	Bemnifosbuvir	AT-511	Others , HCV Protease , SARS-CoV
	Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.		Others , HCV Protease , SARS-CoV
T4474	Asunaprevir	BMS-650032	HCV Protease , SARS-CoV
	Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.		HCV Protease , SARS-CoV
TQ0064	Peretinoin	NIK333	HCV Protease , Retinoid Receptor , S1P Receptor , Autophagy
	Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.		HCV Protease , Retinoid Receptor , S1P Receptor , Autophagy
T9331	Bemnifosbuvir hemisulfate	AT-527	HCV Protease , SARS-CoV
	Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication.		HCV Protease , SARS-CoV
T1822L	Clemizole hydrochloride		HCV Protease , Histamine Receptor
	Clemizole hydrochloride is an antagonist for H1 histamine receptor. According to the research, Clemizole hydrochloride can inhibit hepatitis C virus (HCV) replication and NS4B's RNA binding.		HCV Protease , Histamine Receptor
T0684	Ribavirin	Tribavirin,ICN-1229,NSC-163039,RTCA	Dehydrogenase , HCV Protease , DNA/RNA Synthesis , Antibiotic , AChR , RSV
	Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
T27499	GSK-A1		HCV Protease , PI4K
	GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential.		HCV Protease , PI4K
T3489	Dasabuvir	ABT-333	HCV Protease
	Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra...		HCV Protease
T19073	Tris(4-aminophenyl)methane	Leucopararosaniline	HCV Protease
	Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.		HCV Protease
T6676	Sofosbuvir	GS 7977,PSI-7977	HCV Protease
	Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment of chronic hepatitis C.		HCV Protease
T8930	CID44216842	KUC103479N-02	CDK , Ras
	CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT...		CDK , Ras
T22142	RO8191	RO4948191,CDM-3008	HCV Protease , HBV , JAK , IFNAR , STAT
	RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.		HCV Protease , HBV , JAK , IFNAR , STAT
T6729	Lomibuvir	VX-222,VCH-222	HCV Protease
	Lomibuvir (VCH-222) (VX-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir...		HCV Protease
T12961	Sofosbuvir impurity F	Sofosbuvir 3',5'-Bis-(S)-phosphate	HCV Protease
	Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA replication.		HCV Protease
T6964	Resiquimod	R848,S28463	HCV Protease , TLR
	Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...		HCV Protease , TLR
T2117	PSI-6206	2'-deoxy-2'-fluoro-2'-C-methyluridine,RO 2433,GS-331007	HCV Protease
	PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.		HCV Protease
T19840	GSK-F1	PI4KA inhibitor-F1	PI4K
	GSK-F1 (PI4KA inhibitor-F1) is a novel potent PI4KA inhibitor.		PI4K
T9567	Samatasvir	ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719	HCV Protease
	Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.		HCV Protease
T14667	BLT-1		Others , HCV Protease
	BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.		Others , HCV Protease
T4988	Boceprevir	SCH 503034,EBP 520	HCV Protease , SARS-CoV
	Boceprevir (SCH 503034) is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-based replicon assay.		HCV Protease , SARS-CoV
T22394	Paritaprevir	ABT450,ABT-450,Veruprevir	HCV Protease
	Paritaprevir (ABT450) is an inhibitor of non-structural protein 3/4A protease with EC50 values of 1 and 0.21 nM for HCV 1a and HCV 1b, respectively.		HCV Protease
T4686	Simeprevir	TMC435,TMC-435350,Olysio	HCV Protease , SARS-CoV
	Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.		HCV Protease , SARS-CoV
T2047	AG-1478	AG1478,NSC 693255,Tyrphostin AG-1478	EGFR , HCV Protease , Influenza Virus , HER , PDGFR
	AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.		EGFR , HCV Protease , Influenza Virus , HER , PDGFR

Compounds

Hepatitis Virus C NS3 Protease Inhibitor 2

Target: Others, HCV Protease

Target: Apoptosis, HCV Protease, HBV, TLR, HIV Protease

Coblopasvir dihydrochloride

T25268L

Synonym: Coblopasvir dihydrochloride(1312608-46-0 Free base)

Target: Nucleoside Antimetabolite/Analog, HCV Protease

HCV-IN-30

T11541

Synonym:

Target: Others, HCV Protease

Synonym: VX-497,VI-21497

Target: Dehydrogenase, Antiviral, HCV Protease, HBV

NM107

T7215

Synonym: NM-107,2'-C-Methylcytidine

Target: HCV Protease

Mecarbinate

T0013

Synonym: Dimecarbine,Dimecarbin

Target: HCV Protease

Deferiprone

T1565

Synonym: Deferidone,CP20

Target: Others, HCV Protease, Ferroptosis, UGT

Hepatitis C Virus S5A/5B

Target: HCV Protease, HBV, HIV Protease, Reverse Transcriptase

Clemizole

T1822

Synonym:

Target: HCV Protease, Histamine Receptor

Grazoprevir

T4547

Synonym: MK-5172

Target: HCV Protease, SARS-CoV

Glecaprevir

T5126

Synonym: ABT-493

Target: HCV Protease, SARS-CoV

Ledipasvir

T6200

Synonym: GS-5885

Target: HCV Protease, SARS-CoV

Velpatasvir

T3334

Synonym: GS-5816

Target: HCV Protease, SARS-CoV

FGI-106 tetrahydrochloride

T11281L

Synonym:

Target: Virus Protease, HCV Protease, Influenza Virus, HIV Protease

KIN101

T11760

Synonym: 3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene

Target: HCV Protease, Influenza Virus, RSV, Antifection

Bemnifosbuvir

T9341

Synonym: AT-511

Target: Others, HCV Protease, SARS-CoV

Asunaprevir

T4474

Synonym: BMS-650032

Target: HCV Protease, SARS-CoV

Peretinoin

TQ0064

Synonym: NIK333

Target: HCV Protease, Retinoid Receptor, S1P Receptor, Autophagy

Bemnifosbuvir hemisulfate

T9331

Synonym: AT-527

Target: HCV Protease, SARS-CoV

Clemizole hydrochloride

T1822L

Synonym:

Target: HCV Protease, Histamine Receptor

Ribavirin

T0684

Synonym: Tribavirin,ICN-1229,NSC-163039,RTCA

Target: Dehydrogenase, HCV Protease, DNA/RNA Synthesis, Antibiotic, AChR, RSV

GSK-A1

T27499

Synonym:

Target: HCV Protease, PI4K

Tris(4-aminophenyl)methane

T19073

Synonym: Leucopararosaniline

Target: HCV Protease

Sofosbuvir

T6676

Synonym: GS 7977,PSI-7977

Target: HCV Protease

CID44216842

T8930

Synonym: KUC103479N-02

Target: CDK, Ras

RO8191

T22142

Synonym: RO4948191,CDM-3008

Target: HCV Protease, HBV, JAK, IFNAR, STAT

Lomibuvir

T6729

Synonym: VX-222,VCH-222

Target: HCV Protease

Sofosbuvir impurity F

T12961

Synonym: Sofosbuvir 3',5'-Bis-(S)-phosphate

Target: HCV Protease, TLR

PSI-6206

T2117

Synonym: 2'-deoxy-2'-fluoro-2'-C-methyluridine,RO 2433,GS-331007

Target: HCV Protease

GSK-F1

T19840

Synonym: PI4KA inhibitor-F1

Target: PI4K

Samatasvir

T9567

Synonym: ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719

Target: Others, HCV Protease

Boceprevir

T4988

Synonym: SCH 503034,EBP 520

Target: HCV Protease, SARS-CoV

Paritaprevir

T22394

Synonym: ABT450,ABT-450,Veruprevir

Target: HCV Protease

Simeprevir

T4686

Synonym: TMC435,TMC-435350,Olysio

Target: HCV Protease, SARS-CoV

AG-1478

T2047

Synonym: AG1478,NSC 693255,Tyrphostin AG-1478

Target: EGFR, HCV Protease, Influenza Virus, HER, PDGFR

カタログ番号	製品名	別名	ターゲット
T5S1598	Mulberroside C		Antioxidant , HCV Protease
	1. Mulberroside C has antioxidant activity.		Antioxidant , HCV Protease
T3273	Bifendate	Bifendatatum	HBV , Reverse Transcriptase
	Bifendate (Bifendatatum) is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.		HBV , Reverse Transcriptase
T2770	Gentiopicroside	Gentiopicrin	P450 , HCV Protease
	Gentiopicroside (Gentiopicrin), a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; has antianti-inflammatorya...		P450 , HCV Protease
T3810	Saikosaponin B2		Others , HCV Protease
	Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with...		Others , HCV Protease
TN2089	Platycodin D3		HCV Protease , NF-κB
	Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway mucin; it can significantly enhance mitogen- and OVA-induced...		HCV Protease , NF-κB
T7607	PSI-6130	R 1656	HCV Protease
	PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.		HCV Protease
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T3821	Deapioplatycodin D	Deapi-platycodin D,DesapioplatycodinD	Others , HCV Protease
	Deapioplatycodin D and platycodin D can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extract of APG as expectorants in diverse inflammatory pulmonar...		Others , HCV Protease
T2S1158	4,5-Dicaffeoylquinic acid	3,4-Dicaffeoylquinic acid,Isochlorogenic acid C	Others , HBV , Endogenous Metabolite
	1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.		Others , HBV , Endogenous Metabolite
T0392	Artemisinin	Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine	HCV Protease , Ferroptosis , Akt , Parasite
	Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organisms, including chloroquine-resistant Plasmodium ...		HCV Protease , Ferroptosis , Akt , Parasite
T1188	Mizoribine	Bredinin,NSC 289637,HE 69	HCV Protease , SARS-CoV , Tyrosinase
	Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.		HCV Protease , SARS-CoV , Tyrosinase
T7203	Oglufanide	L-Glutamyl-L-tryptophan,H-Glu-Trp-OH	VEGFR , HCV Protease , Endogenous Metabolite
	Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).		VEGFR , HCV Protease , Endogenous Metabolite
T7060	Amantadine	1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine	Others
	Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.		Others
TN1033	Sennidin A		HCV Protease , transporter , Akt , PI3K
	Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.		HCV Protease , transporter , Akt , PI3K
TN1034	Sennidin B		HCV Protease , transporter , Akt , PI3K
	Sennidin B stimulates glucose incorporation in rat adipocytes.		HCV Protease , transporter , Akt , PI3K
TN6732	Oenothein B		Apoptosis , HCV Protease , Antibacterial , Antifungal
	Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.		Apoptosis , HCV Protease , Antibacterial , Antifungal
T38375	Pseudane IX	2-nonyl-4-hydroxyquinoline,2-nonyl-1H-quinolin-4-one,2-nonyl-4(1h)-quinolone	HCV Protease
	Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml.		HCV Protease
TN2185	Schisantherin C		Others
	Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.		Others
TN5079	Sulochrin		HCV Protease , Antifection
	Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotoxicity up to 50 uM. Sulochrin has an inhibitory activity to ...		HCV Protease , Antifection
TN3809	Dehydrojuncusol		HCV Protease
	Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is active against resistant HCV variants frequently found in patie...		HCV Protease
TN4404	Ladanein		HCV Protease
	Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays m...		HCV Protease
TN3438	Arborinine		HCV Protease , Antifection
	Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0.7 ug/ml. Arborinine shows antifeedant activity against Spod...		HCV Protease , Antifection

天然物製品

Mulberroside C

T5S1598

Synonym:

Target: Antioxidant, HCV Protease

Bifendate

T3273

Synonym: Bifendatatum

Target: HBV, Reverse Transcriptase

Gentiopicroside

T2770

Synonym: Gentiopicrin

Target: P450, HCV Protease

Saikosaponin B2

T3810

Synonym:

Target: Others, HCV Protease

Platycodin D3

TN2089

Synonym:

Target: HCV Protease, NF-κB

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Deapioplatycodin D

T3821

Synonym: Deapi-platycodin D,DesapioplatycodinD

Target: Others, HCV Protease

4,5-Dicaffeoylquinic acid

T2S1158

Synonym: 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C

Target: Others, HBV, Endogenous Metabolite

Artemisinin

T0392

Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine

Target: HCV Protease, Ferroptosis, Akt, Parasite

Mizoribine

T1188

Synonym: Bredinin,NSC 289637,HE 69

Target: HCV Protease, SARS-CoV, Tyrosinase

Oglufanide

T7203

Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

Target: VEGFR, HCV Protease, Endogenous Metabolite

Amantadine

T7060

Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine

Target: HCV Protease, transporter, Akt, PI3K

Sennidin B

TN1034

Synonym:

Target: HCV Protease, transporter, Akt, PI3K

Oenothein B

TN6732

Synonym:

Target: Apoptosis, HCV Protease, Antibacterial, Antifungal

Pseudane IX

T38375

Synonym: 2-nonyl-4-hydroxyquinoline,2-nonyl-1H-quinolin-4-one,2-nonyl-4(1h)-quinolone

Target: HCV Protease, Antifection

Target: HCV Protease, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01564	Hepatitis C virus (HCV-1a) E2 Protein (His)	HCV	HEK293
	Hepatitis C virus (HCV-1a) E2 Protein (His) is expressed in HEK293 with His tag. The predicted molecular weight is 32 kDa. Accession number: NP_751921.1
TMPY-00296	Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His)	HCV	HEK293
	Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His) is expressed in HEK293 with His tag. The predicted molecular weight is 32.2 kDa. Accession number: BAA03581.1
TMPY-05166	Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His)	HCV	HEK293
	Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His) is expressed in HEK293 with His tag. The predicted molecular weight is 32.4 kDa. Accession number: AAC15723.1
TMPY-04135	Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)	HCV	HEK293
	Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) is expressed in HEK293 with His tag. The predicted molecular weight is 18.7 kDa. Accession number: AAC15725.1
TMPY-00323	Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)	HCV	E. coli
	HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B...
TMPJ-01273	ACY3 Protein, Human, Recombinant (His)	Human	E. coli
	Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2, Aspartoacylase-2, HCV core-binding protein 1 and ASPA2, is a member ...
TMPY-00772	DC-SIGN Protein, Human, Recombinant (hFc)	Human	HEK293
	Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable...
TMPY-05542	ASGR1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR...
TMPY-02702	ASGR1 Protein, Human, Recombinant (His)	Human	HEK293
	The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR...
TMPY-00463	ENPP2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-02778	ENPP2 Protein, Human, Recombinant (His)	Human	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-01032	CD299 Protein, Human, Recombinant (hFc)	Human	HEK293
	C-type lectin domain family 4, member M, also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to DC-SIGN, an HIV gp120-binding protein. Though the encoded gene locate...
TMPY-02285	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein	H1N1	E. coli
	Non-structural protein 2 (NS2) plays a crucial role in the hepatitis C virus (HCV) assembly. NS2 was predicted to be composed of three transmembrane (TM) segments. Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is...
TMPH-00848	OASL Protein, Human, Recombinant (His)	Human	E. coli
	Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RN...
TMPH-01548	IFI6 Protein, Human, Recombinant (B2M & His)	Human	E. coli
	Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis. However, it has also been shown to have a pro-apoptotic activity. Has an antiviral activity towar...
TMPH-02131	SKP2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle pr...
TMPY-04715	DC-SIGN Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable...
TMPY-04714	DC-SIGN Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable...
TMPY-06943	ASGR1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR...
TMPY-05349	ASGR1 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293
	The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR...
TMPY-00671	ASGR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR...
TMPH-01555	IFITM1 Protein, Human, Recombinant (GST)	Human	E. coli
	IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against ...
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPH-01249	ADAR Protein, Human, Recombinant (GST)	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPH-01556	EIF2AK2 Protein, Human, Recombinant (His)	Human	Yeast
	IFN-induced dsRNA-dependent serine/threonine-protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) and plays a key role in the innate immune response to v...
TMPY-02055	ENPP2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-04231	CD299 Protein, Human, Recombinant	Human	HEK293
	C-type lectin domain family 4, member M, also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to DC-SIGN, an HIV gp120-binding protein. Though the encoded gene locate...
TMPH-01604	SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptop...
TMPH-01073	CD81 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalizati...
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...

Hepatitis C virus (HCV-1a) E2 Protein (His)

TMPY-01564

Species: HCV

Expression System: HEK293

Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His)

TMPY-00296

Species: HCV

Expression System: HEK293

Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His)

TMPY-05166

Species: HCV

Expression System: HEK293

Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)

TMPY-04135

Species: HCV

Expression System: HEK293

Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)

TMPY-00323

Species: HCV

Expression System: E. coli

ACY3 Protein, Human, Recombinant (His)

TMPJ-01273

Species: Human

Expression System: E. coli

DC-SIGN Protein, Human, Recombinant (hFc)

TMPY-00772

Species: Human

Expression System: HEK293

ASGR1 Protein, Human, Recombinant (His), Biotinylated

TMPY-05542

Species: Human

Expression System: HEK293

ASGR1 Protein, Human, Recombinant (His)

TMPY-02702

Species: Human

Expression System: HEK293

ENPP2 Protein, Cynomolgus, Recombinant (His)

TMPY-00463

Species: Cynomolgus

Expression System: HEK293

ENPP2 Protein, Human, Recombinant (His)

TMPY-02778

Species: Human

Expression System: HEK293

CD299 Protein, Human, Recombinant (hFc)

TMPY-01032

Species: Human

Expression System: HEK293

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein

TMPY-02285

Species: H1N1

Expression System: E. coli

OASL Protein, Human, Recombinant (His)

TMPH-00848

Species: Human

Expression System: E. coli

IFI6 Protein, Human, Recombinant (B2M & His)

TMPH-01548

Species: Human

Expression System: E. coli

SKP2 Protein, Human, Recombinant (His & SUMO)

TMPH-02131

Species: Human

Expression System: E. coli

DC-SIGN Protein, Rhesus, Recombinant (His)

TMPY-04715

Species: Rhesus

Expression System: HEK293

DC-SIGN Protein, Rhesus, Recombinant (hFc)

TMPY-04714

Species: Rhesus

Expression System: HEK293

ASGR1 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06943

Species: Human

Expression System: HEK293

ASGR1 Protein, Mouse, Recombinant (His), Biotinylated

TMPY-05349

Species: Mouse

Expression System: HEK293

ASGR1 Protein, Mouse, Recombinant (His)

TMPY-00671

Species: Mouse

Expression System: HEK293

IFITM1 Protein, Human, Recombinant (GST)

TMPH-01555

Species: Human

Expression System: E. coli

ADAR Protein, Human, Recombinant (His & SUMO)

TMPH-01248

Species: Human

Expression System: E. coli

ADAR Protein, Human, Recombinant (GST)

TMPH-01249

Species: Human

Expression System: E. coli

EIF2AK2 Protein, Human, Recombinant (His)

TMPH-01556

Species: Human

Expression System: Yeast

ENPP2 Protein, Mouse, Recombinant (His)

TMPY-02055

Species: Mouse

Expression System: HEK293

CD299 Protein, Human, Recombinant

TMPY-04231

Species: Human

Expression System: HEK293

SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)

TMPH-01604

Species: Human

Expression System: E. coli

CD81 Protein, Human, Recombinant (His & SUMO)

TMPH-01073

Species: Human

Expression System: E. coli

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01456

Species: Human

Expression System: HEK293

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01450

Species: Human

Expression System: HEK293

HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

TMPK-01451

Species: Human

Expression System: HEK293

カタログ番号	製品名
L1720	Nucleotide Compound Library		334 compounds
	A unique collection of 334 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs;

ライブラリー

Nucleotide Compound Library

L1720

Compounds: 334